Methylmercury and Neurotoxicity

Methylmercury and Neurotoxicity

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Mercury (Hg) is a global pollutant that knows no environmental boundaries. Even the most stringent control of anthropogenic Hg sources will not eliminate exposure given its ubiquitous presence. Exposure to Hg occurs primarily via the food chain due to MeHga€™s accumulation in fish. Latest US statistics indicate that 46 States have fish consumption advisories. In addition, Hg is a common pollutant in hazardous waste sites, with an estimated 3-4 million children living within one mile of at least one of the 1, 300+ active hazardous waste sites in the US. The effects on intellectual function in children prenatally exposed to MeHg via maternal fish consumption have been the subject of two on-going major, prospective, longitudinal studies in the Seychelles and the Faroe Islands. It is important to recognize that the risk for MeHg exposure is not limited only to islanders with high fish consumption. This book will provide state-of-the-art information to the graduate student training in toxicology, risk assessors, researchers and medical providers at large. It is aimed to bring the reader up to date on contemporary issues associated with exposure to methylmercury, from its effects on stem cells and neurons to population studies.manifested neurological signs characteristic of methylmercury poisoning, a follow -up study revealed a much larger ... detectable in the most sensitive individuals at blood mercury concentrations of 200a€“500 mg/L and hair concentrations from 50 to ... positive associations of hair mercury concentration with visual contrast sensitivity and manual dexterity (Lebel et al. ... Data from a 1977 cross-sectional study on 302 Quebec Cree adults (Canadian aboriginal population) for whom fish is aanbsp;...

Title:Methylmercury and Neurotoxicity
Author: Sandra Ceccatelli, Michael Aschner
Publisher:Springer Science & Business Media - 2012-03-23

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